(853) The Combination of the Ratio of Tricuspid Annular Plane Systolic Excursion to Systolic Pulmonary Arterial Pressure and Reveal Lite 2.0 in Early Prediction of Disease Progression of Pulmonary Arterial Hypertension

PurposeOur prior findings demonstrated the additive value of echocardiographic parameters - specifically left ventricle end diastolic (LV ED) eccentricity index to REVEAL lite 2.0 in early prediction disease progression pulmonary arterial hypertension (PAH). The latest 2022 ESC/ERS PH guidelines suggested use Tricuspid Annular Plane Systolic Excursion Pulmonary Arterial Pressure (TAPSE/sPAP) as a predictor right ventricle-pulmonary artery (RV-PA) coupling and outcomes. In response, we performed secondary analysis determine whether TAPSE/sPAP combined with is superior our previously published findings.MethodsWe single-center retrospective 74 patients PAH who had Lite score, well echocardiography between January 2016 December 2019. A multivariable regression was using alone compared combining different parameters, including TAPSE/sPAP.ResultsThe majority were women, WHO class II-III, either idiopathic or connective tissue related PAH. for found be AUC 0.73 (CI = 0.60, 0.86). Adding improved 0.78 0.66, 0.90).ConclusionIn this small cohort analysis, adding C statistics detection event. Our findings. We TAPSE/sPAP. 0.90).